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doi: 10.3389/fnut.2025.1754492 Received 26 November 2025 Revised 20 December 2025 Accepted 24 December 2025 Published 21 January 2026 Volume 12 - 2025 Edited by Javier Diaz-Castro, University of Granada, Spain Reviewed by Mahsa Rezazadegan, Isfahan University of Medical Sciences, Iran Soroush Taherkhani, Iran University of Medical Sciences, Iran Updates Copyright © 2026 Poon, Li, Schweitzer and Akefe
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Two other studies demonstrated that MAPK pathway inhibitors in combination with HDACi suppressed cAMP mediated resistance in melanoma cells [109] and that pre-treatment of platinum drug resistant ovarian cancer cells with HDACi and methylation inhibitors sensitized these cells to cisplatin-mediated cell death [110]
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