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We also provide in vitro data which identifies the capacity of (1) microglia to release Hexβ and (2) neurons to take up Hexβ and integrate it into the lysosomal compartment

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Categorical analyses of weight loss outcomes showed that higher proportions of participants in the Cagrilintide groups achieved at least 5%, 10%, and 15% weight reductions compared to placebo, with results generally comparable to liraglutide