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Two independent experiments were completed, bars represent means and symbols (□, ○) represent individual experiments

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The composition according to any of claims 1 -886, wherein the one or more pharmamers comprises biotinylated recombinant HLA class 2 protein HLA-DFT0401 and recombinant HSP70pep3Bio fragments (a biotinylated HSP70 fragment spanning amino acid residues 359-609) attached to strepavidin sites