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Blood 115 , 1572–1581 (2010)

thiamine HCl injection

Tablets:30 Tablets

Because FOXO4-DRI’s mechanism depends on disrupting the FOXO4–p53 interaction, and because this interaction is only operative in cells with elevated FOXO4 expression, the compound preferentially targets the senescent cell population — leaving FOXO4-low non-senescent cells largely unaffected