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The authors attempted also to elucidate the underlying mechanisms highlighting that H19 directly interacted with the Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (4E-BP1), at the TOS motif inhibiting competitively its binding to Raptor

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Additionally, acetylation modification of the P53 DNA-binding region can regulate SLC7A11 expression, thereby promoting ferroptosis in certain cancer cells [9]

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