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Several studies have demonstrated that TGF-β has protective or promotive effects on intestinal barrier function.58 In intestinal T84 cells, TGF-β increases the basal TER, which is mediated by claudin-1 expression through MEK/ERK signaling

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Research has shown that AOD-9604 increases the expression of beta-3 adrenergic receptors in adipose tissue, restoring suppressed receptor levels in obese models