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Keywords: presbycusis, age-related hearing loss (ARHL), hair cells (HCs), spiral ganglion neurons (SGN), reactive oxygen species (ROS), c-Jun terminal kinase (JNK), inflammation, cell survival signaling Introduction Acquired Sensorineural Hearing Loss (SNHL) Sensorineural hearing loss (SNHL) is a common sensory deficit, the WHO estimating in 2012 that globally over 360 million people have disabling hearing loss (Duthey, 2013)
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