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They demonstrate that the combination of the long-acting amylin agonist cagrilintide plus the GLP-1 RA semaglutide, when combined as a single injection once weekly in people with type 2 diabetes, offers increased glucose lowering and significant weight reduction compared with semaglutide 2.4 mg (the licensed dose for weight loss) used alone

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Estrogen supplementation decreases norepinephrine-induced vasoconstriction and total body norepinephrine spillover in perimenopausal women