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What the controlled human sleep trials show is more measured: a double-blind study in chronic insomniacs found improved sleep efficiency and faster sleep onset, though the effects were modest, and later attempts to reproduce the earliest dramatic results were inconsistent.[17] The fair read is that DSIP is a real endogenous sleep-and-stress signal with a tantalizing profile whose human potential is still being worked out — an investigational molecule with genuine promise and unfinished homework, not a solved equation