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In summary, abnormal ferroptosis signaling pathways leading to reduced neurotransmitter synthesis, lipid peroxide accumulation, mitochondrial dysfunction, and increased release of pro-inflammatory factors are important factors contributing to decreased neural plasticity, delayed synaptic growth and development, impaired neural network conduction, and neurotoxicity, ultimately leading to depression

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[DOI] [Google Scholar] 61.Meguid N.A., Ghozlan S.A.S., Mohamed M.F., Ibrahim M.K., Dawood R.M., Din N.G.B.E., Abdelhafez T.H., Hemimi M., El Awady M.K