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Gypenoside IX suppresses p38 MAPK/Akt/NFkappaB signaling pathway activation and inflammatory responses in astrocytes stimulated by proinflammatory mediators

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Although this latter study using Dm GPx was based on high-definition crystallographic data for GPx-4, molecular modeling suggests that the Asn may also be essential in GPx-1 (359) and that the functional catalytic site is actually a tetrad