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Finally, it’s important to work with a practitioner to address any underlying causes, such as hypothyroidism or anatomical issues, to ensure long-term success

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found that Notch inhibition increased hair cell regeneration by Lgr5 -positive cells in the neonatal cochlea in vitro (Bramhall et al., 2014), implying that Wnt-responsive cells are prevented by Notch signaling to differentiate into hair cells