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Additional symptoms seen in neonates with this form of CPT2 deficiency include hydrocephalus, cerebral calcifications, agenesis of the corpus callosum, cerebellar vermian hypoplasia, polymicrogyria, pachygyria, as well as other neuronal migration defects

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Le Sermorelin se lie au récepteur de la GHRH (GHRHR), un récepteur couplé aux protéines G exprimé par les cellules somatotropes de l'hypophyse antérieure