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Finally, to reveal whether NSI‐189 induced secretion of neurogenic factors in cultured hippocampal cells which might have facilitated cell proliferation and neurogenesis, we measured from the conditioned media (harvested from NSI‐189 supplemented and standard growth medium) trophic factors such as SCF, brain derived‐neurotrophic factor (BDNF), glial cell line‐derived neurotrophic factor (GDNF), and vascular endothelial growth factor (VEGF) which have been implicated as critical secretory factors associated with stemness properties (Lladó, Haenggeli, Maragakis, Snyder, & Rothstein, 2004
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Review current studies exploring GHK-Cu’s effects on reproductive health In vitro, GHK-Cu has been demonstrated to reduce markers of oxidative stress in granulosa and Sertoli cell lines, potentially preserving follicles and spermatogenic support cells
