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Moreover, it has been found that the dopaminergic fibers arising from the ventral tegmental area (VTA) project to the prefrontal cortex (PFC) and to regions of the limbic system, such as the nucleus accumbens (NAcc), forming the mesocorticolimbic (MCL) circuit

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Radiation and Medication Having a history of radiation exposure, especially to the neck area, or taking certain medications can also increase the risk of developing hypothyroidism