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In a high-fat diet-treated mice model with a double knockout of the LDL receptor (LDL-R −/− ), a significant elevation of serum lipids including TC, TG, and LDL was observed in the non-treated mice, and the serum levels of these lipids were significantly reduced by oral administration of TQ at 50 mg/kg/day (60)

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Brain injury causes astrogliosis, an early marker of neurotoxicity, characterized by an increased expression of GFAP and the release of bioactive molecules that can modulate the neurotoxic effects of organophosphorus pesticides (Young et al