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Schiller’s group discovered that the outer shell of human papillomavirus (HPV) binds the outsides of cancer cells but not healthy cells
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siRNA-mediated knockdown of GLS1 in both the lymphoma and prostate cancer cell lines resulted in reduced ATP levels, diminished glutathione levels, and increased levels of ROS, firmly establishing glutamine metabolism as a target of c-Myc and as a potential target for cancer therapeutics
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