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Patients meeting inclusion criteria after exclusion were identified from a prospective database held for audit and research purposes

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Other activities of ROS in plants include direct pathogen killing, cell wall construction, and programmed cell death activation, in addition to promoting the activation of defense genes (Mhamdi and Van Breusegem, 2018) ROS have been shown to inhibit cell division in yeast and mammalian cells, and ROS has been shown to inhibit cell cycle progression (Qi and Zhang, 2020) The revelation that O2- plays an important role in the battle against invading germs, effectively serving as a broad-spectrum antibiotic, offers as a crystal-clear and forceful demonstration of how ROS may be used for good (Bardaweel et al., 2018) Plants respond to pathogen invasion with a number of defensive mechanisms, including a “oxidative burst” that creates massive amounts of ROS quickly and transiently (Kapoor et al., 2019) As a result, ROS plays several, and often contradictory, functions throughout diverse cellular processes