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Endocytosis The process of taking up materials from outside the cells into intracellular vesicles called endosomes

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The authors wish to thank Dr Patrick Fueger (Comprehensive Metabolic Phenotyping Core Facility) for assistance in the indirect calorimetry studies, Dr Lu Yang and Dr Xiwei Wu (Integrative Genomics and Bioinformatics Core) and Dr Yate-Ching Yuan (Division of Research Informatics) for the help in RNA sequencing data analyses and database submission, and Mrs