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If the diagnosis of neuropsychological manifestations of vitamin B12 deficiency is delayed, symptoms may become irreversible [7,8,9] within variable time intervals (months to years), depending on residual B12 stores in the liver
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One year later, the same authors could show that this nutraceutical formulation causes that the 24 individuals diagnosed with AD, which received this supplementation for 12 months under open-label conditions, maintained their baseline cognitive performance and behavioral and psychological symptoms of dementia [189]
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