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Of particular note, the researchers reported that lower levels of CD320 or dietary B 12 restriction worsened the disease course in an animal model of MS and reduced the therapeutic efficacy of fingolimod, which occurred through a mechanism in which fingolimod hitchhikes by binding to the TCN2-B12 complex, allowing delivery of all to the astrocytes via interactions with CD320, with component losses disrupting the process and worsening disease
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A colonoscopy found two polyps (benign) which were removed and an endoscopy found " patchy gastric metaplasia " and " flattened mucosal pattern at D1 and D2 " (duodenum) but once Coeliac disease was ruled out, nothing more was said about that
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