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For instance, network-based analyses of a Danshen (Salvia) multi-component formula identified nine key compounds collectively modulating 42 cardiovascular-related genes, highlighting how a mixture’s efficacy arises from multi-target synergy (Li et al., 2011)

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[DOI] [PMC free article] [PubMed] [Google Scholar] Chemin A., Lam J., Laurens G., Trichard F., Motto-Ros V., Ledoux G., Jarý V., Laguta V., Nikl M., Dujardin C