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Furthermore, phosphorylation of Ser351 within p62, which is observed in both human hepatocellular carcinoma and autophagy-deficient mouse liver, enables p62 to interact with two additional residues within the Kelch domain, which further enhances its ability to compete with NRF2 for KEAP1 binding (Table 3) (146, 147)
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Contenance:60 Gélules | 30 Doses
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