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Additionally, CoQ10 binds to the mitochondrial permeability transition pore, preventing mitochondrial depolarization and cytochrome C release to lower cysteine protease-3 activation and reduce apoptosis (Hseu et al., 2018

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Normally, Fe 3+ -metHb is converted back to its reduced form by cytochrome b5 reductase, according to the following reaction: However, under sustained oxidative stress conditions, the amount of NADH reducing equivalent declines