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Considering the prevalence of vascular disorders is increasing globally, it is imperative that these regulatory mechanisms are exploited therapeutically in order to bring about progress in the treatment of vascular disorders

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It is characterized by the overproduction of extracellular senile plaques composed of the β-amyloid peptide (Aβ), the aggregation of hyperphosphorylated tau protein, and the selective loss of neurons in neuropathology [2,3]