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Emerging evidence has unveiled the pivotal role of iron in orchestrating tumor cell proliferation and implicating its potential influence on breast cancer progression through interference with distinct cell death mechanisms, including ferroptosis 6,7

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Notably, geographic disparities exist in prevalence trends: high-income countries demonstrate plateauing incidence rates of allergic disorders, whereas low- and middle-income nations face escalating trends, potentially reflecting environmental and socioeconomic determinants (Genuneit and Standl, 2022)