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Through these evolutionarily conserved stress response programs, fasting has been observed to extend life span in Escherichia coli, Saccharomyces cerevisiae, Caenorhabditis elegans, and mice and to decrease IGF-1 in mice and humans (54)
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Conclusion: MFH compounds are promising, hypothesis-generating candidates for adjunctive nutrition in PD, pending clinical dose–response and long-term safety validation
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