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Compared with DHB, AAN demonstrates higher sensitivity for detecting PL classes in negative ion mode by generating more negative ions, which enhances sensitivity and significantly improves reproducibility while reducing acquisition time

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In an in vitro model of cardiovascular diseases, 6-shogaol was shown to protect endothelial cells from oxidized LDL-induced apoptosis by reducing ROS production and inhibiting caspase-9 and caspase-3 activation, and upregulating the antiapoptotic protein Bcl-2