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The overall epiphytic lifestyle also includes upregulation of genes to counter oxidative stress and repair or degrade damaged proteins, reduce osmotic stress through potassium pumps, synthesize cellulose, type II toxin-antitoxin systems, copper resistance proteins, the Type VI Secretion System, and genes suggesting a greater focus on cyclic-di-GMP synthesis compared to degradation
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532 Recent efforts identified 184 high confidence intracellular NO 2 -FA targets in macrophages, expanding the reported list to include such important targets as the retinoid X receptor and Toll-like receptors
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